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Table 4 National- and international guidelines: corticosteroid treatment in case of COPD exacerbation

From: COPD exacerbations in general practice: variability in oral prednisolone courses

Guideline Recommendation
NHG- guideline COPD 2007 • Prednisolone 30 mg once a day for 7-14 days.
CBO guideline 2010:
Diagnostics and treatment of COPD
• Prednisolone 30 mg once a day for 7-14 days.
• Prefer oral prednisolone treatment.
• Blood sugar check for patients with diabetes.
GOLD guideline 2009 'Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease' • Prednisolone 30-40 mg once a day for 7-10 days for patients with FEV1 < 50%
• Budesonide, whether or not combined with formoterol may be an alternative to prednisolone treatment.
• Prefer oral prednisolone treatment
ATS/ERS guideline 2004 'Standards for the diagnosis and treatment of patients with COPD' • 30-40 mg prednisolone once a day for 10 days.
• Consider corticosteroid inhalation therapy.
Nice guideline 2010: 'Chronic obstructive pulmonary disease: Management of chronic obstructive pulmonary disease in adults in primary and secondary care'. • Prednisolone 30 mg once a day for 7-14 days.