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Table 2 Prevalence [%, (n)] of chronic conditions and medication use among people reporting NSAID use

From: Cause for concern in the use of non-steroidal anti-inflammatory medications in the community -a population-based study

 

Reported NSAID use

  

Ns-NSAID

  

COX-2 inhibitor

  
 

No

Yes

p

No

Yes

 

No

Yes

 

Chronic conditions, % (n)

         

Joint pain

         

Diagnosed as arthritis

23.4 (649)

70.8 (247)

< 0.01

26.9 (796)

57.5 (100)

< 0.01

25.3 (745)

83.4 (151)

< 0.01

Not diagnosed as arthritis

39.4 (1095)

22.6 (79)

 

37.8 (1117)

32.8 (57)

 

39.0 (1151)

12.7 (23)

 

Cardiovascular disease/stroke

8.7 (240)

17.2 (60)

< 0.01

9.4 (276)

13.8 (24)

0.05

9.0 (264)

20.0 (36)

< 0.01

MI/angina

6.5 (182)

12.0 (42)

< 0.01

7.0 (208)

9.2 (16)

0.28

6.7 (198)

14.4 (26)

< 0.01

> 15% 10 year CVD risk

14.9 (324)

20.7 (56)

0.01

15.4 (355)

17.9 (25)

0.44

15.1 (348)

23.7 (32)

< 0.01

Hypertension*

40.3 (1137)

60.8 (217)

< 0.01

42.0 (1261)

52.8 (93)

< 0.01

41.0 (1226)

68.4 (128)

< 0.01

Kidney disease**

20.6 (576)

30.8 (109)

< 0.01

21.6 (644)

23.4 (41)

0.58

20.8 (616)

37.3 (69)

< 0.01

Primary care provider visits in previous year

         

0

7.9 (219)

2.3 (8)

< 0.01

7.4 (220)

4.0 (7)

< 0.01

7.7 (226)

0.6 (1)

< 0.01

1-4

53.0 (1474)

29.4 (103)

 

51.5 (1521)

32.2 (56)

 

51.9 (1530)

26.0 (47)

 

≥ 5

39.1 (1087)

68.3 (239)

 

41.1 (1215)

63.8 (111)

 

40.5 (1193)

73.5 (133)

 

Medications

         

Anti-hypertensives

26.6 (749)

40.9 (146)

< 0.01

27.9 (836)

33.5 (59)

0.11

27.0 (806)

47.6 (89)

< 0.01

Diuretics

3.6 (101)

9.0 (32)

< 0.01

4.1 (123)

5.7 (10)

0.31

3.7 (110)

12.3 (23)

< 0.01

ACE inhibitors

11.3 (319)

12.0 (43)

0.69

11.2 (336)

14.8 (26)

0.15

11.5 (344)

9.6 (18)

0.43

Gastro-esophageal reflux

12.3 (347)

31.9 (114)

< 0.01

14.0 (419)

23.9 (42)

< 0.01

12.9 (386)

40.1 (75)

< 0.01

  1. *Hypertension: systolic ≥ 140 mm Hg and/or diastolic ≥ 90 mm Hg or use of anti-hypertensive medication.
  2. **Kidney disease: GFR < 60 ml/min/1.73 m2, GFR > 60 and proteinuria.