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Table 5 Sensitivity, specificity and NPV of cardiovascular biomarkers in relation to the working and confirmed diagnoses.

From: Diagnostic accuracy of point-of-care testing for acute coronary syndromes, heart failure and thromboembolic events in primary care: a cluster-randomised controlled trial

Biomarker Working/Confirmed diagnosis Sensitivity Specificity NPV
   n % n % n %
cTnT Working ACS 11/26 42 113/121 93 113/128 88
  Confirmed ACS 10/17 59 121/130 93 121/128 95
NT-proBNP Working HF 33/35 94 26/35 74 26/28 93
  Confirmed HF 31/31 100 28/39 72 28/28 100
D-dimer Working TE 16/20 80 78/98 80 78/82 95
  Confirmed TE 13/14 93 81/104 78 81/82 99
  1. (i) ACS, acute coronary syndromes; cTnT, cardiac troponin T; HF, heart failure; NPV, negative predictive value; NT-proBNP, N-terminal pro-brain natriuretic peptide; TE, thromboembolic events.