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Table 3 Prescription of combination therapy according to age group and gender

From: Evaluation of prescribing patterns in a German network of CAM physicians for the treatment of patients with hypertension: a prospective observational study

Antihypertensives

Total

Gender

Age group [years]

  

Male

Female

Under 40

40-59

60-79

80 or older

 

[N (%)]

[n (%)]

[n (%)]

[n (%)]

[n (%)]

[n (%)]

[n (%)]

2-drug combinations

845 (100)

288 (100)

557 (100)

29 (100)

192 (100)

470 (100)

154 (100)

Diuretic plus

       

Beta-blocker

       

   - Fixed-dose coformulation

67 (7.9)

12 (4.1)

55 (9.9)

5 (17.2)

19 (9.9)

33 (7.0)

10 (6.5)

   - Monopreparation

53 (6.3)

15 (5.2)

38 (6.8)

1 (3.4)

19 (9.9)

24 (5.1)

9 (5.8)

CCB1

       

   - Fixed-dose coformulation

1 (0.1)

1 (0.3)

-

-

-

1 (0.2)

-

   - Monopreparation

30 (3.6)

11 (3.8)

19 (3.4)

-

3 (1.6)

15 (3.2)

12 (7.8)

ACE inhibitor

       

   - Fixed-dose coformulation

208 (24.6)

72 (25.0)

136 (24.4)

1 (3.4)

41 (21.4)

128 (27.2)

38 (24.7)

   - Monopreparation

56 (6.6)

23 (8.0)

33 (5.9)

-

9 (4.7)

32 (6.8)

15 (9.7)

Angiotensin II antagonist

       

   - Fixed-dose coformulation

207 (24.5)

55 (19.1)

152 (27.3)

2 (6.9)

45 (23.4)

126 (26.8)

34 (22.1)

   - Monopreparation

11 (1.3)

1 (0.3)

10 (1.8)

-

2 (1.0)

5 (1.1)

4 (2.6)

CCBs plus

       

Beta-blocker

       

   - Fixed-dose coformulation

-

-

-

-

-

-

-

   - Monopreparation

38 (4.5)

13 (4.5)

25 (4.5)

10 (34.5)

4 (2.1)

20 (4.3)

4 (2.6)

ACE inhibitor

       

   - Fixed-dose coformulation

1 (0.1)

1 (0.3)

-

-

-

1 (0.2)

-

   - Monopreparation

30 (3.6)

11 (3.8)

19 (3.4)

1 (3.4)

9 (4.7)

16 (3.4)

4 (2.6)

Angiotensin II antagonist

       

   - Fixed-dose coformulation

-

-

-

-

-

-

-

   - Monopreparation

20 (2.4)

9 (3.1)

11 (2.0)

-

4 (2.1)

14 (3.0)

2 (1.3)

Beta-blockers plus

       

Other antihypertensive

       

   - Fixed-dose coformulation

5 (0.6)

-

5 (0.9)

-

-

4 (0.9)

1 (6.0)

   - Monopreparation

81 (9.6)

52 (18.1)

29 (5.2)

7 (24.1)

33 (17.2)

33 (7.0)

8 (5.2)

Other

37 (4.4)

12 (4.2)

25 (4.5)

2 (6.9)

4 (2.1)

18 (3.8)

13 (8.4)

3-drug combinations

104 (100)

58 (100)

46 (100)

3 (100)

31 (100)

58 (100)

12 (10)

Diuretic plus ACE inhibitor plus CCB

       

   - Monopreparation

       
 

2 (1.9)

2 (3.4)

-

-

-

1 (1.7)

1 (8.3)

Diuretic plus beta-blocker plus 2

       

   - Monopreparation

57 (54.8)

27 (46.6)

30 (65.2)

1 (33.3)

20 (64.5)

30 (51.7)

6 (50.0)

Diuretic plus antiadrenergic agents plus 2

       

   - Monopreparation

       
 

6 (5.8)

5 (8.6)

1 (2.2)

-

4 (12.9)

2 (3.4)

-

Other

39 (37.5)

24 (41.4)

15 (32.6)

2 (66.7)

7 (22.6)

25 (43.1)

5 (41.7)

  1. 1 Calcium channel blocker, 2 CCB, ACE inhibitor, angiotensin II antagonist, alpha-blocker, or dihydrazine
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