Skip to main content

Advertisement

Table 4 Diagnostic performance of the 4DSQ distress scale and the HADS total score with respect to detecting any depressive or anxiety disorder (prevalence 61%)*

From: Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the Hospital Anxiety and Depression Scale (HADS)

4DSQ distress sensitivity specificity PPV NPV
≥16 0.95 0.37 0.70 0.83
≥17 0.94 0.43 0.72 0.82
≥18 0.93 0.47 0.73 0.81
≥19 0.91 0.55 0.76 0.79
≥20 0.90 0.56 0.76 0.78
≥21 0.84 0.57 0.76 0.70
≥22 0.77 0.67 0.78 0.65
≥23 0.75 0.67 0.78 0.63
≥24 0.71 0.73 0.80 0.61
≥25 0.65 0.77 0.82 0.59
≥26 0.61 0.80 0.83 0.57
≥27 0.56 0.84 0.85 0.55
≥28 0.48 0.85 0.83 0.51
≥29 0.36 0.90 0.85 0.48
≥30 0.28 0.94 0.88 0.46
≥31 0.19 0.97 0.90 0.43
HADS total score
≥16 0.96 0.41 0.72 0.86
≥17 0.93 0.46 0.73 0.80
≥18 0.92 0.50 0.74 0.80
≥19 0.89 0.59 0.77 0.78
≥20 0.86 0.64 0.79 0.74
≥21 0.82 0.68 0.80 0.71
≥22 0.76 0.75 0.82 0.66
≥23 0.71 0.80 0.85 0.64
≥24 0.63 0.84 0.86 0.59
≥25 0.56 0.85 0.85 0.55
≥26 0.46 0.88 0.85 0.51
≥27 0.39 0.89 0.84 0.48
≥28 0.32 0.91 0.85 0.46
≥29 0.27 0.92 0.84 0.45
≥30 0.21 0.95 0.86 0.43
  1. * For each scale three cut-off points are highlighted in bold type: the optimal cut-off point with the best balance between sensitivity and specificity, the best lower cut-off point with a sensitivity ≥0.85, and the best higher cut-off point with a specificity ≥0.85
  2. 4DSQ = Four-Dimensional Symptom Questionnaire
  3. HADS = Hospital Anxiety and Depression Scale
  4. PPV = positive predictive value
  5. NPV = negative predictive value